Endocrine Abstracts

Background: The influence of hyperinsulinemia and insulin resistance on thyroid function is debatable. Insulin, as an anabolic hormone, may also play a role in thyroid hypertrophy and nodular goitre development. Some recent reports focus on the possible interplay between thyroid function and glucose status in pregnancy, including gestational diabetes mellitus.Aim: The study aimed to assess the relationship between insulin resistance indices and thyroid f...

Introduction: Treatment with somatostatin analogues (SSA) leads to shrinkage of pituitary adenoma in acromegaly naïve patients, as shown by the PRIMARYS study. Therefore the effect of this treatment on surgery was investigated.Aim: To evaluate the efficacy of pre-treatment with SSA in acromegaly patients qualified for neurosurgery.Material and methods: Group A (46 patients: 36 female, 10 male) were pre-treated with SSA. Group ...

IntroductionAcromegaly is a chronic, slowly progressing disease caused in most cases by growth hormone (GH)- producing pituitary neuroendocrine tumors (PitNETs). This rare disorder is associated with a spectrum of various clinical manifestations and treatment outcomes differ between patients. The aim of this study was to evaluate the impact of age at the onset of symptoms and sex on clinical features, comorbidities, biochemical status at the diagnosis, a...

The reference ranges of thyroid function tests during pregnancy are still being debated, even in ethnically homogenous populations. The defining of the normal range is of importance, as it influences therapeutic decisions, particularly the use (or over-use) of levothyroxine in this vulnerable population. The study was aimed at the longitudinal assessment of thyroid function tests results in marginally iodine sufficient Polish population of pregnant women. The study was perform...

The solitary fibrous tumor is a rare spindle cell neoplasm, originally described in the pleural cavity. However, it can occur in other locations. SFTs that originate from the adrenal gland tissue are extremely rare. To date, only single cases have been described in the literature. We present a case of a 61-year-old Caucasian man with a SFT of the left adrenal gland. The patient was hospitalized in the internal medicine department due to paroxysmal hypertension (up to 190/100 m...